BIOMEDICINE: Resisting Renegade Cells

: Resisting History

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Resisting Explanation

Although explanation is widely regarded as an important concept in the study of rational inquiry, it remains largely unexplored outside the philosophy of science. This, I believe, is not due to oversight as much as to institutional resistance. In analytic philosophy it is basic that epistemic rationality is a function of justification and that justification is a function of argument. Explanatio...

Tropical Biomedicine

Biomedicine Select

Autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, are complex disorders characterized by an inflammatory response against the body's own tissues. Recent findings reveal new insights into how these diseases are initiated and progress and the factors that contribute to their clinical symptoms. Such work also pinpoints potential new therapeutic targets including the integra...

Biomedicine Select

This issue’s Biomedicine Select highlights new insights into the role of mitochondria in disease. Several new studies implicate abnormal mitochondria in the destruction of neurons of the substantia nigra, the cause of Parkinson’s disease (PD). Meanwhile, an elegant computational approach has enabled identification of candidate genes for several mitochondrial diseases including the mitochondrial...